A rapid detection method for Vaccinia virus, the surrogate for smallpox virus
نویسندگان
چکیده
منابع مشابه
A rapid detection method for Vaccinia virus, the surrogate for smallpox virus.
Prior to the World Health Organization's announcement of total eradication in 1977 [J. Am. Med. Assoc. 281 (1999) 1735], smallpox was a worldwide pathogen. Vaccinations were ceased in 1980 and now with a largely unprotected world population, smallpox is considered the ideal biowarfare agent [Antiviral Res. 57 (2002) 1]. Infection normally occurs after implantation of the virus on the oropharyng...
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The threat of smallpox release and use as a bioweapon has encouraged the search for new vaccines and antiviral drugs, as well as development of new small-animal models in which their efficacy can be determined. Here, we reinvestigate a rabbit model in which the intradermal infection of rabbits with very low doses of either rabbitpox virus (RPV) or vaccinia virus Western Reserve (VV-WR) recapitu...
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ژورنال
عنوان ژورنال: Biosensors and Bioelectronics
سال: 2004
ISSN: 0956-5663
DOI: 10.1016/j.bios.2004.01.029